2022 Mercedes-Benz S580 4matic Maybach MPG
EPA-rated · verified snapshot 2026-08-30 · Large Cars
The 2022 Mercedes-Benz S580 4matic Maybach gets 18 MPG combined — 15 city and 24 highway — in its most efficient configuration (4.0L · 8-cyl · Automatic 9-spd · All-Wheel Drive · Hybrid).
City15 MPG
Highway24 MPG
$4,200Fuel cost / yr (EPA est.)
484 g/miCO₂
PremiumFuel
$-10,0005-yr fuel cost vs. average vehicle
3 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
118 ft³Passenger volume
Where it sits among sedans (2022)
Compared with the 2021 model, the 2022 S580 4matic Maybach is -1 MPG worse at its best.
FAQ
Is 18 MPG good for a sedans like the 2022 S580 4matic Maybach?
The 2022 S580 4matic Maybach's 18 MPG combined is below the sedans average of 33.2 MPG for 2022.
How much does it cost to fuel a 2022 S580 4matic Maybach per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $4,200 for the most efficient trim.
What is the city and highway MPG of the 2022 S580 4matic Maybach?
The most efficient trim is rated 15 MPG city and 24 MPG highway.