HomeMercedes-BenzC300 4matic2010

2010 Mercedes-Benz C300 4matic MPG

EPA-rated · verified snapshot 2026-08-30 · Compact Cars

The 2010 Mercedes-Benz C300 4matic gets 20 MPG combined — 18 city and 25 highway — in its most efficient configuration (3.0L · 6-cyl · Automatic 7-spd · 4-Wheel Drive · FFV).

20COMBINED MPG
City18 MPG
Highway25 MPG
$3,800Fuel cost / yr (EPA est.)
444 g/miCO₂
Premium or E85Fuel
$-8,0005-yr fuel cost vs. average vehicle
12 ft³Cargo volume
88 ft³Passenger volume
Where it sits among compact cars (2010)

Every 2010 C300 4matic trim

ConfigurationCityHwyComb.$/yr
3.0L · 6-cyl · Automatic 7-spd · 4-Wheel Drive · FFV182520$3,800
3.5L · 6-cyl · Automatic 7-spd · 4-Wheel Drive172420$3,800

FAQ

Is 20 MPG good for a compact cars like the 2010 C300 4matic?
The 2010 C300 4matic's 20 MPG combined is below the compact cars average of 22.4 MPG for 2010.
How much does it cost to fuel a 2010 C300 4matic per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,800 for the most efficient trim.
What is the city and highway MPG of the 2010 C300 4matic?
The most efficient trim is rated 18 MPG city and 25 MPG highway.