2024 Mercedes-Benz E450 4matic All-Terrain MPG
EPA-rated · verified snapshot 2026-08-30 · Midsize Station Wagons
The 2024 Mercedes-Benz E450 4matic All-Terrain gets 25 MPG combined — 22 city and 31 highway — in its most efficient configuration (3.0L · 6-cyl · Automatic 9-spd · All-Wheel Drive · Hybrid).
City22 MPG
Highway31 MPG
$3,050Fuel cost / yr (EPA est.)
351 g/miCO₂
PremiumFuel
$-4,2505-yr fuel cost vs. average vehicle
5 / 10EPA Fuel Economy & GHG score
33 ft³Cargo volume
102 ft³Passenger volume
Where it sits among sedans (2024)
Compared with the 2023 model, the 2024 E450 4matic All-Terrain is +1 MPG better at its best.
FAQ
Does the 2024 E450 4matic All-Terrain get good gas mileage for its class?
The 2024 E450 4matic All-Terrain's 25 MPG combined is below the sedans average of 45.5 MPG for 2024.
How much does it cost to fuel a 2024 E450 4matic All-Terrain per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,050 for the most efficient trim.
What is the city and highway MPG of the 2024 E450 4matic All-Terrain?
The most efficient trim is rated 22 MPG city and 31 MPG highway.