2003 Mercedes-Benz S500 4matic MPG
EPA-rated · verified snapshot 2026-08-30 · Large Cars
The 2003 Mercedes-Benz S500 4matic gets 16 MPG combined — 14 city and 19 highway — in its most efficient configuration (5.0L · 8-cyl · Automatic 5-spd · 4-Wheel or All-Wheel Drive).
City14 MPG
Highway19 MPG
$4,750Fuel cost / yr (EPA est.)
555 g/miCO₂
PremiumFuel
$-12,7505-yr fuel cost vs. average vehicle
15 ft³Cargo volume
106 ft³Passenger volume
Where it sits among sedans (2003)
FAQ
Is 16 MPG good for a sedans like the 2003 S500 4matic?
The 2003 S500 4matic's 16 MPG combined is below the sedans average of 19.9 MPG for 2003.
How much does it cost to fuel a 2003 S500 4matic per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $4,750 for the most efficient trim.
What is the city and highway MPG of the 2003 S500 4matic?
The most efficient trim is rated 14 MPG city and 19 MPG highway.