2023 Mercedes-Benz S500 4matic MPG
EPA-rated · verified snapshot 2026-08-30 · Large Cars
The 2023 Mercedes-Benz S500 4matic gets 23 MPG combined — 20 city and 28 highway — in its most efficient configuration (3.0L · 6-cyl · Automatic 9-spd · All-Wheel Drive · Hybrid).
City20 MPG
Highway28 MPG
$3,300Fuel cost / yr (EPA est.)
388 g/miCO₂
PremiumFuel
$-5,5005-yr fuel cost vs. average vehicle
5 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
112 ft³Passenger volume
Where it sits among sedans (2023)
Compared with the 2022 model, the 2023 S500 4matic is -1 MPG worse at its best.
FAQ
Is 23 MPG good for a sedans like the 2023 S500 4matic?
The 2023 S500 4matic's 23 MPG combined is below the sedans average of 36.6 MPG for 2023.
How much does it cost to fuel a 2023 S500 4matic per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,300 for the most efficient trim.
What is the city and highway MPG of the 2023 S500 4matic?
The most efficient trim is rated 20 MPG city and 28 MPG highway.