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2008 Mercedes-Benz C300 MPG

EPA-rated · verified snapshot 2026-08-30 · Compact Cars

The 2008 Mercedes-Benz C300 gets 21 MPG combined — 18 city and 26 highway — in its most efficient configuration (3.0L · 6-cyl · Manual 6-spd · Rear-Wheel Drive).

21COMBINED MPG
City18 MPG
Highway26 MPG
$3,600Fuel cost / yr (EPA est.)
423 g/miCO₂
PremiumFuel
$-7,0005-yr fuel cost vs. average vehicle
12 ft³Cargo volume
88 ft³Passenger volume
Where it sits among compact cars (2008)

Every 2008 C300 trim

ConfigurationCityHwyComb.$/yr
3.0L · 6-cyl · Manual 6-spd · Rear-Wheel Drive182621$3,600
3.0L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive · FFV182521$3,600

FAQ

Where does the 2008 C300 rank among compact cars for MPG?
The 2008 C300's 21 MPG combined is below the compact cars average of 21.1 MPG for 2008.
How much does it cost to fuel a 2008 C300 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,600 for the most efficient trim.
What is the city and highway MPG of the 2008 C300?
The most efficient trim is rated 18 MPG city and 26 MPG highway.