2010 Mercedes-Benz C300 MPG
EPA-rated · verified snapshot 2026-08-30 · Compact Cars
The 2010 Mercedes-Benz C300 gets 21 MPG combined — 18 city and 26 highway — in its most efficient configuration (3.0L · 6-cyl · Manual 6-spd · Rear-Wheel Drive).
City18 MPG
Highway26 MPG
$3,600Fuel cost / yr (EPA est.)
423 g/miCO₂
PremiumFuel
$-7,0005-yr fuel cost vs. average vehicle
12 ft³Cargo volume
88 ft³Passenger volume
Where it sits among compact cars (2010)
Every 2010 C300 trim
| Configuration | City | Hwy | Comb. | $/yr |
|---|---|---|---|---|
| 3.0L · 6-cyl · Manual 6-spd · Rear-Wheel Drive | 18 | 26 | 21 | $3,600 |
| 3.0L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive · FFV | 18 | 26 | 21 | $3,600 |
| 3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive | 18 | 26 | 21 | $3,600 |
FAQ
Where does the 2010 C300 rank among compact cars for MPG?
The 2010 C300's 21 MPG combined is below the compact cars average of 22.4 MPG for 2010.
How much does it cost to fuel a 2010 C300 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,600 for the most efficient trim.
What is the city and highway MPG of the 2010 C300?
The most efficient trim is rated 18 MPG city and 26 MPG highway.