2022 Mercedes-Benz C300 MPG
EPA-rated · verified snapshot 2026-08-30 · Compact Cars
The 2022 Mercedes-Benz C300 gets 29 MPG combined — 25 city and 35 highway — in its most efficient configuration (2.0L · 4-cyl · Automatic 9-spd · Rear-Wheel Drive · Hybrid).
City25 MPG
Highway35 MPG
$2,600Fuel cost / yr (EPA est.)
305 g/miCO₂
PremiumFuel
$-2,0005-yr fuel cost vs. average vehicle
6 / 10EPA Fuel Economy & GHG score
12 ft³Cargo volume
93 ft³Passenger volume
Where it sits among compact cars (2022)
Compared with the 2021 model, the 2022 C300 is +2 MPG better at its best.
FAQ
Where does the 2022 C300 rank among compact cars for MPG?
The 2022 C300's 29 MPG combined is above the compact cars average of 28.2 MPG for 2022.
How much does it cost to fuel a 2022 C300 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $2,600 for the most efficient trim.
What is the city and highway MPG of the 2022 C300?
The most efficient trim is rated 25 MPG city and 35 MPG highway.