2021 Mercedes-Benz C300 MPG
EPA-rated · verified snapshot 2026-08-30 · Compact Cars
The 2021 Mercedes-Benz C300 gets 27 MPG combined — 23 city and 35 highway — in its most efficient configuration (2.0L · 4-cyl · Automatic 9-spd · Rear-Wheel Drive).
City23 MPG
Highway35 MPG
$2,800Fuel cost / yr (EPA est.)
324 g/miCO₂
PremiumFuel
$-3,0005-yr fuel cost vs. average vehicle
6 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
90 ft³Passenger volume
Where it sits among compact cars (2021)
Compared with the 2020 model, the 2021 C300 is -1 MPG worse at its best.
FAQ
Where does the 2021 C300 rank among compact cars for MPG?
The 2021 C300's 27 MPG combined is below the compact cars average of 27.3 MPG for 2021.
How much does it cost to fuel a 2021 C300 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $2,800 for the most efficient trim.
What is the city and highway MPG of the 2021 C300?
The most efficient trim is rated 23 MPG city and 35 MPG highway.