2027 Mercedes-Benz S580 4matic MPG
EPA-rated · verified snapshot 2026-08-30 · Large Cars
The 2027 Mercedes-Benz S580 4matic gets 19 MPG combined — 16 city and 24 highway — in its most efficient configuration (4.0L · 8-cyl · Automatic 9-spd · All-Wheel Drive · Hybrid).
City16 MPG
Highway24 MPG
$4,000Fuel cost / yr (EPA est.)
464 g/miCO₂
PremiumFuel
$-9,0005-yr fuel cost vs. average vehicle
4 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
112 ft³Passenger volume
Where it sits among sedans (2027)
Compared with the 2026 model, the 2027 S580 4matic is -1 MPG worse at its best.
FAQ
Is 19 MPG good for a sedans like the 2027 S580 4matic?
The 2027 S580 4matic's 19 MPG combined is below the sedans average of 48.1 MPG for 2027.
How much does it cost to fuel a 2027 S580 4matic per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $4,000 for the most efficient trim.
What is the city and highway MPG of the 2027 S580 4matic?
The most efficient trim is rated 16 MPG city and 24 MPG highway.