2007 Mercedes-Benz E350 MPG
EPA-rated · verified snapshot 2026-08-30 · Midsize Cars
The 2007 Mercedes-Benz E350 gets 19 MPG combined — 17 city and 24 highway — in its most efficient configuration (3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive).
City17 MPG
Highway24 MPG
$4,000Fuel cost / yr (EPA est.)
468 g/miCO₂
PremiumFuel
$-9,0005-yr fuel cost vs. average vehicle
14 ft³Cargo volume
97 ft³Passenger volume
Where it sits among sedans (2007)
Compared with the 2006 model, the 2007 E350 is -1 MPG worse at its best.
FAQ
Does the 2007 E350 get good gas mileage for its class?
The 2007 E350's 19 MPG combined is below the sedans average of 20.1 MPG for 2007.
How much does it cost to fuel a 2007 E350 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $4,000 for the most efficient trim.
What is the city and highway MPG of the 2007 E350?
The most efficient trim is rated 17 MPG city and 24 MPG highway.