2011 Mercedes-Benz E350 MPG
EPA-rated · verified snapshot 2026-08-30 · Midsize Cars
The 2011 Mercedes-Benz E350 gets 20 MPG combined — 17 city and 25 highway — in its most efficient configuration (3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive).
City17 MPG
Highway25 MPG
$3,800Fuel cost / yr (EPA est.)
444 g/miCO₂
PremiumFuel
$-8,0005-yr fuel cost vs. average vehicle
14 ft³Cargo volume
97 ft³Passenger volume
Where it sits among sedans (2011)
Compared with the 2010 model, the 2011 E350 is -1 MPG worse at its best.
FAQ
Does the 2011 E350 get good gas mileage for its class?
The 2011 E350's 20 MPG combined is below the sedans average of 21.8 MPG for 2011.
How much does it cost to fuel a 2011 E350 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,800 for the most efficient trim.
What is the city and highway MPG of the 2011 E350?
The most efficient trim is rated 17 MPG city and 25 MPG highway.