2020 Mercedes-Benz E350 MPG
EPA-rated · verified snapshot 2026-08-30 · Midsize Cars
The 2020 Mercedes-Benz E350 gets 26 MPG combined — 23 city and 32 highway — in its most efficient configuration (2.0L · 4-cyl · Automatic 9-spd · Rear-Wheel Drive).
City23 MPG
Highway32 MPG
$2,900Fuel cost / yr (EPA est.)
336 g/miCO₂
PremiumFuel
$-3,5005-yr fuel cost vs. average vehicle
5 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
98 ft³Passenger volume
Where it sits among sedans (2020)
FAQ
Does the 2020 E350 get good gas mileage for its class?
The 2020 E350's 26 MPG combined is below the sedans average of 30.5 MPG for 2020.
How much does it cost to fuel a 2020 E350 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $2,900 for the most efficient trim.
What is the city and highway MPG of the 2020 E350?
The most efficient trim is rated 23 MPG city and 32 MPG highway.