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2013 Mercedes-Benz E350 MPG

EPA-rated · verified snapshot 2026-08-30 · Midsize Cars

The 2013 Mercedes-Benz E350 gets 23 MPG combined — 20 city and 29 highway — in its most efficient configuration (3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive).

23COMBINED MPG
City20 MPG
Highway29 MPG
$3,300Fuel cost / yr (EPA est.)
385 g/miCO₂
PremiumFuel
$-5,5005-yr fuel cost vs. average vehicle
6 / 10EPA Fuel Economy & GHG score
13 ft³Cargo volume
98 ft³Passenger volume
Where it sits among sedans (2013)

Every 2013 E350 trim

ConfigurationCityHwyComb.$/yr
3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive202923$3,300
3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive192923$3,300
3.5L · 6-cyl · Automatic 7-spd · Rear-Wheel Drive · FFV202923$3,300

FAQ

Does the 2013 E350 get good gas mileage for its class?
The 2013 E350's 23 MPG combined is below the sedans average of 24.6 MPG for 2013.
How much does it cost to fuel a 2013 E350 per year?
Based on EPA assumptions (15,000 miles/year), estimated annual fuel cost is $3,300 for the most efficient trim.
What is the city and highway MPG of the 2013 E350?
The most efficient trim is rated 20 MPG city and 29 MPG highway.